Spinal manipulation therapy for mild arthritis
- Produce immediate relief of and significantly decrease acute and chronic neck and back pain and reduce pain by neural mechanisms at higher brain areas.
- Increase range of motion of the spine and improve posture and spinal proprioception.
- Decrease peripheral and central sensitization, increase lowered pain threshold and reduce increased sensitivity to pain.
- More effective versus analgesic medications (pain killers) in treating muscle-joint pain disorders with fewer side-effects than nonsteroidal anti-inflammatory drugs (NSAIDs).
Localized Cryostimulation therapy for arthritis
- Decrease the frequency and degree of pain perception and the use of pain killers and improve the range of physical activity and well-being in osteoarthritis of the spine and peripheral joints.
- Produce beneficial effects in sciatica, and ankylosing spondylitis arthritis of the spine confirmed through thermovision.
- Decrease pro-inflammatory tumor necrosis factor and increase anti-inflammatory interleukin-6 in individuals who have rheumatoid arthritis.
- Equals to two weeks of traditional rehabilitation and therapeutic modalities to reduce pain, disability, and disease activity, including kinesiotherapy, magneto-therapy, electrotherapy, ultrasound, and laser therapy.
- Compared to conventional rehabilitation, kinesiotherapy reduces pain, decreases disease activity, improves locomotor (movement) function, and has long-lasting effects.
- Decrease histamine levels, a compound released by cells in response to injury and allergic and inflammatory reactions, versus four weeks of conventional physiotherapy.
- Decrease serum inflammatory markers, decrease total oxidative status and increase total antioxidant status.
- Decrease pain twice as much, decrease disease activity, and improve functional outcomes and quality of life in people with arthritis versus kinesiotherapy.
- Improve spinal mobility in individuals suffering from ankylosing spondylitis.
- Decrease pain and improve functional outcomes in individuals with Magnetic Resonance Imaging (MRI) confirmed intervertebral herniation disc.
Localized Cryostimulation therapy for osteoporosis
- Decrease pain and swellings, cause skeletal muscles, and increase muscle power and range of motion in individuals with symptomatic osteoporosis.
- Enhance average and healthy bone turnover in osteopenia and osteoporosis, significantly decreasing the serum bone-turnover marker osteocalcin and increasing carboxyterminal cross-linked telopeptide of type I collagen.
- Increase remodelling osteoimmunological biomarkers osteoprotegerin and counteracts the altered osteoclast activity with decreased bone resorption and decreased osteolytic disease progression.
- Decrease oxidative stress and increase the anti-oxidative buffering capacities in healthy individuals, especially those suffering from musculoskeletal diseases; antioxidant therapy could alleviate the adverse effects of oxidative stress in osteoporosis.
- Decrease pain and improve functional outcomes individuals with Magnetic Resonance Imaging (MRI) confirmed intervertebral herniation disc as a possible consequence of osteoporosis.
Current global issues
- Arthritis, osteoporosis, and other rheumatic disorders are increasingly becoming an alarming physical, social and economic burden causing moderate to severe disability worldwide.
- Musculoskeletal-rheumatic disorders are often difficult to treat, with limited conservative treatment options and poor prognosis.
- Rheumatic and musculoskeletal conditions comprise over 150 diseases and progressive syndromes, which are amongst the most widespread painful and disabling pathologies across the globe.
- The most significant impact on society is osteoarthritis, a degenerative joint disease, and rheumatoid arthritis, a chronic inflammatory joint autoimmune disease.
- Rheumatic diseases, in particular osteoarthritis, can no longer be labelled as “degenerative” diseases; growing evidence supports the role of inflammation and neuroinflammation, not only locally, in promoting damage to the spine, joints, and bones, as well as joint-related functional deficits. Inflammation is a necessary protective defence mechanism of the human being against injury and infection; the inflammatory response function to localize and eliminate the harmful agent, protect the injured tissue from further damage, and remove damaged tissue components the body can heal itself.
- Excessive and chronic inflammation and oxidative stress play a vital role in the pathophysiology (cause) of inflammatory joint diseases and osteoporosis. Free radicals are toxic by-products of oxygen metabolism that can cause severe damage to living cells and tissues in a process known as oxidative stress and play a vital role in the pathophysiology of inflammatory joint diseases and osteoporosis.
- Oxidative stress may play a significant role in the pathogenesis of osteoporosis and serve as an essential aggravating factor for osteopenia, osteoporosis, and insufficiency fractures; the antioxidant systems present in the human body prevent oxidative stress.
- Pain itself manifest as a complex biopsychosocial problem: the inability to move efficiently as well as the neck and back pain itself affect a human’s expectations of self-efficacy, that is, a human being’s belief in their ability to complete tasks and reach goals as it is associated with detrimental changes in mood, sleep, coping skills and lower financial income.
- Unwanted pharmaceutical adverse effects for mechanical back pain: chronic mechanical back pain is becoming a significant health issue concerning increased and regular pharmaceutical usage.
Current issues regarding arthritis
- Osteoarthritis in young, active, and athletic individuals are rapidly rising; osteoarthritis is one of the most devastating chronic conditions that previously in the majority affect the middle to the old-age world population.
- Osteoarthritis of the knee has doubled in the last decade due to recent exponential increases in life expectancy, obesity, and sedentary lifestyle; one of the most common joint diseases and leading causes of disability.
Current issues regarding osteoporosis
- There is an exponential increasing incidence of osteoporosis-related symptomatic fractures: osteoporosis is the most common bone disease affecting humans with a significant physical, social, and financial burden.
- Physical therapy is challenging and problematic: due to the risk to induce insufficiency fracture; low bone density results from altered bone resorption and formation homeostasis and bone turnover.
- The osteoclast activity surpasses osteoblast activity: typically, there are no symptoms unless the condition progresses to osteoporosis; symptoms of osteoporosis include back pain, loss of height, a stooped posture, and easily fractured bones.
